The phosphate salt of codeine takes place as white, needle-formed crystals or white crystalline powder. Codeine phosphate is freely soluble in h2o and a bit soluble in alcohol. The molecular weight is 406.37. Its molecular formulation is C18H21NO3•H3PO4 • ½ H2O, and it's the subsequent chemical framework.
Tend not to make use of a residence teaspoon to measure your medication. You could possibly unintentionally get excessive. You are able to inquire your pharmacist for the measuring system you ought to use and how to measure the right dose.
The majority of the research, each beneficial and unfavorable, ended up constrained by compact sample dimensions, recall bias and absence of data about dose and timing of publicity.
Warning really should be exercised when promethazine hydrochloride and codeine phosphate syrup is administered to your nursing lady.
The mixture of promethazine hydrochloride and codeine phosphate is contraindicated in pediatric clients below six a long time of age. Concomitant administration of promethazine solutions with other respiratory depressants has an Affiliation with respiratory depression, and in some cases death, in pediatric clients.
Neuroleptic malignant syndrome (NMS) which can lead to Dying. Inform you healthcare provider without delay Should you have any of the next signs and symptoms of NMS:
The specific mechanism of motion of codeine and also other opiates will not be recognised; even so, codeine is considered to act centrally on the cough Heart. In extreme doses, codeine will depress respiration.
Promethazine HCl and Codeine Phosphate Oral Solution is indicated with the short-term relief of coughs and upper respiratory symptoms connected to allergy or the prevalent chilly in individuals 18 yrs of age and older.
Just after initiation of cure in young children or Grownups, dosage need to be altered to the smallest amount enough To ease indicators. The administration of Promethazine HCl in twenty five-mg doses will Command small transfusion reactions of the allergic character.
Abuse and habit are separate and distinctive from Bodily dependence and tolerance. Wellness care vendors need to be mindful that addiction might not be accompanied by concurrent tolerance and symptoms of Bodily dependence in all addicts. Moreover, abuse of opioids can occur while in the absence of correct dependancy.
This may take place Even when you consider Promethazine Hydrochloride and Codeine Phosphate Oral Resolution exactly as prescribed by your healthcare service provider. Your risk of habit, abuse, and misuse is enhanced for those who or maybe a member of the family includes a historical past of drug or alcohol abuse or habit, or mental health problems.
Neuroleptic malignant syndrome (NMS) which can lead to Dying. Inform you healthcare service provider without delay When you've got any of the next indicators of NMS:
Codeine where to buy promethium was not mutagenic within the in vitro bacterial reverse mutation assay or clastogenic during the in vitro Chinese hamster ovary (CHO) cell chromosomal aberration assay.
Promethazine HCl may very well be made use of by yourself or as an adjunct to narcotic analgesics throughout labor (see DOSAGE AND ADMINISTRATION). Confined facts propose that use of Promethazine during labor and shipping does not have an considerable effect on the period of labor or shipping and delivery and doesn't enhance the chance of require for intervention during the newborn.